KLF2 antibody (Middle Region)

Catalog No. ABIN2777573

Product Details anti-KLF2 Antibody

Target: KLF2 (Kruppel-Like Factor 2 (Lung) (KLF2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Sequence: PPAFGLFDDA AAAAAALGLA PPAARGLLTP PASPLELLEA KPKRGRRSWP

Predicted Reactivity: Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against KLF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLF2 antibody (ABIN2777573)

Yamada, Park, Mamonkin, Lacorazza: "Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2." in: Nature immunology, Vol. 10, Issue 6, pp. 618-26, (2009) (PubMed).

Target Details for KLF2

Target: KLF2 (Kruppel-Like Factor 2 (Lung) (KLF2))

Alternative Name: KLF2 (KLF2 Products)

Synonyms: LKLF antibody, Lklf antibody, lklf antibody, MGC52512 antibody, klf2 antibody, cb125 antibody, sb:cb125 antibody, zgc:91780 antibody, Kruppel like factor 2 antibody, Kruppel-like factor 2 (lung) antibody, Kruppel-like factor 2 antibody, Kruppel-like factor 2 S homeolog antibody, Krueppel-like factor 2 antibody, Kruppel-like factor 2b antibody, KLF2 antibody, Klf2 antibody, klf2.S antibody, klf2 antibody, klf2b antibody

Background: KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.
Alias Symbols: LKLF
Protein Interaction Partner: KAT2B, EP300, CREBBP, FBXW7, UBC, GSK3B, ELAVL1, SMURF1, WWP1, GATA5, GATA6, WEE1,
Protein Size: 355

Molecular Weight: 37 kDa

Gene ID: 10365

NCBI Accession: NM_016270, NP_057354

UniProt: Q9Y5W3