HMG20A antibody (Middle Region)

Catalog No. ABIN182661

Product Details anti-HMG20A Antibody

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMG20A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RKTQDRQKGK SHRQDAARQA THDHEKETEV KERSVFDIPI FTEEFLNHSK

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMG20A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMG20A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMG20A

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Alternative Name: HMG20A (HMG20A Products)

Background: HMG20A plays a role in neuronal differentiation as chromatin-associated protein. HMG20A acts as inhibitor of HMG20B. HMG20A overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. HMG20A involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4
Alias Symbols: HMGX1, HMGXB1
Protein Interaction Partner: RSPH9, CFAP53, SYTL4, SCNM1, CCDC136, RPP30, HMG20A, PTH2R, KPNA2, HPCAL1, DTNB, FMNL1, ADD1, BRAP, UBC, HECW2, HTT, HDAC2, HDAC1, MTA3, KDM1A, SMAD4, ELAVL1, GTF2A1L, TESC, RBM7, CCNK, MAGOHB,
Protein Size: 347

Molecular Weight: 40 kDa

Gene ID: 10363

NCBI Accession: NM_018200, NP_060670

UniProt: Q9NP66