Mafg antibody (Middle Region)

Catalog No. ABIN2777530

Product Details anti-Mafg Antibody

Target: Mafg (Transcription Factor MafG (Mafg))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mafg antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MAFG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAFG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 162 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Mafg

Target: Mafg (Transcription Factor MafG (Mafg))

Alternative Name: MAFG (Mafg Products)

Synonyms: zgc:85896 antibody, MAFG antibody, hMAF antibody, AA545192 antibody, C630022N07Rik antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb antibody, MAF bZIP transcription factor G antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) antibody, mafgb antibody, MAFG antibody, Mafg antibody

Background: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2.
Alias Symbols: MGC13090, MGC20149, hMAF
Protein Interaction Partner: NFE2L2, PARP1, MAFG, DDIT3, BACH1, ATF3, BACH2, BATF3, MAFF, NFE2L3, NFIL3, NFE2L1, PIDD1, UBC, SNRPN, HSP90AA1, HIF1A, CYP2E1, SUMO1, SUMO2, SUMO3, PPP1CA, GTF2A1L, MED31, RBM48, CHD3, NFE2, PAX6, CREBBP, VIM, MAF, PRRX1, HOXD12,
Protein Size: 162

Molecular Weight: 18 kDa

Gene ID: 4097

NCBI Accession: NM_002359, NP_002350

UniProt: O15525