ZBTB48 antibody (N-Term)

Catalog No. ABIN2777508

Product Details anti-ZBTB48 Antibody

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB48 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDGSFVQHSV RVLQELNKQR EKGQYCDATL DVGGLVFKAH WSVLACCSHF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZBTB48. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZBTB48

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 688 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZBTB48 antibody (ABIN2777508)

Kim, Chadalapaka, Pathi, Jin, Lee, Park, Cho, Chintharlapalli, Safe: "Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters." in: Molecular cancer therapeutics, Vol. 11, Issue 9, pp. 1852-62, (2012) (PubMed).

Target Details for ZBTB48

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Alternative Name: ZBTB48 (ZBTB48 Products)

Background: ZBTB48 contains 1 BTB (POZ) domain and 11 C2H2-type zinc fingers. It belongs to the krueppel C2H2-type zinc-finger protein family and binds to and regulates the J and/or S elements in MHC II promoter.
Alias Symbols: HKR3, pp9964, ZNF855
Protein Interaction Partner: ZBTB8A, KRTAP10-5, GPATCH2L, NME7, ZBTB48, ZBTB7A, EP300, UPF2, CDK2AP2, TNFRSF14, RGS2, ILK, CDKN1A, PNRC2, NUDT21, C11orf58, C7orf34, ZBTB8B, DVL3,
Protein Size: 688

Molecular Weight: 77 kDa

Gene ID: 3104

NCBI Accession: NM_005341, NP_005332

UniProt: P10074