NKX2-8 antibody (C-Term)

Catalog No. ABIN2777459

Product Details anti-NKX2-8 Antibody

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX2-8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTAAAQEKCG APPAAACPLP GYPAFGPGSA LGLFPAYQHL ASPALVSWNW

Predicted Reactivity: Cow: 92%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NKX2-8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NKX2-8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 239 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Alternative Name: NKX2-8 (NKX2-8 Products)

Synonyms: NKX2.8 antibody, NKX2H antibody, Nkx2-9 antibody, Nkx-2.9 antibody, Nkx2-8 antibody, Nkx2.9 antibody, tinman antibody, NK2 homeobox 8 antibody, NK2 homeobox 9 antibody, NKX2-8 antibody, Nkx2-9 antibody, Nkx2-8 antibody

Background: A murine NKX2-8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. Nkx2.8 bound to the active AFP promoter, and antisense inhibition of Nkx2.8 mRNA translation selectively reduced expression of both the endogenous human AFP gene and transfected reporters containing the rat AFP promoter.
Alias Symbols: NKX2.8, NKX2H, Nkx2-9
Protein Interaction Partner: NKX2-8,
Protein Size: 239

Molecular Weight: 26 kDa

Gene ID: 26257

NCBI Accession: NM_014360, NP_055175

UniProt: O15522