SOX1 antibody (Middle Region)

Catalog No. ABIN2777427

Product Details anti-SOX1 Antibody

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rabbit, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAGGAHQNSA VAAAAAAAAA SSGALGALGS LVKSEPSGSP PAPAHSRAPC

Predicted Reactivity: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against SOX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 391 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX1

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Alternative Name: SOX1 (SOX1 Products)

Synonyms: BB176347 antibody, Sox-1 antibody, XlSox1 antibody, xSox1 antibody, wu:fi38c08 antibody, wu:fj38h03 antibody, zgc:92865 antibody, SRY-box 1 antibody, SRY (sex determining region Y)-box 1 antibody, SRY-box 1 S homeolog antibody, SRY (sex determining region Y)-box 1b antibody, SRY box 1 antibody, SRY (sex determining region Y)-box 1a antibody, SOX1 antibody, Sox1 antibody, sox1.S antibody, sox1b antibody, sox1a antibody

Background: SOX1 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX1 may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
Alias Symbols: -
Protein Interaction Partner: CTNNB1,
Protein Size: 391

Molecular Weight: 39 kDa

Gene ID: 6656

NCBI Accession: NM_005986, NP_005977

UniProt: O00570