KDM2A antibody (N-Term)

Catalog No. ABIN2777419

Product Details anti-KDM2A Antibody

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RIRYSQRLRG TMRRRYEDDG ISDDEIEGKR TFDLEEKLHT NKYNANFVTF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against FBXL11. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 782 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Alternative Name: FBXL11 (KDM2A Products)

Synonyms: FBXL11 antibody, JHDM1A antibody, 100043628 antibody, 5530401A10Rik antibody, AA589516 antibody, AW536790 antibody, Cxxc8 antibody, Fbl11 antibody, Fbl7 antibody, Fbxl11 antibody, Gm4560 antibody, Jhdm1 antibody, Jhdm1a antibody, lalina antibody, KDM2A antibody, CXXC8 antibody, FBL11 antibody, FBL7 antibody, LILINA antibody, fb76b11 antibody, wu:fb76b11 antibody, wu:fj11c04 antibody, zgc:158441 antibody, zgc:158606 antibody, lysine demethylase 2A antibody, lysine (K)-specific demethylase 2A antibody, lysine (K)-specific demethylase 2Aa antibody, KDM2A antibody, Kdm2a antibody, kdm2aa antibody

Background: FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats
Alias Symbols: FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA
Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
Protein Size: 782

Molecular Weight: 86 kDa

Gene ID: 22992

NCBI Accession: NM_001256405

Pathways: Warburg Effect