SP7 antibody (C-Term)

Catalog No. ABIN2777381

Product Details anti-SP7 Antibody

Target: SP7 (Sp7 Transcription Factor (SP7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RTHGEPGPGP PPSGPKELGE GRSTGEEEAS QTPRPSASPA TPEKAPGGSP

Predicted Reactivity: Cow: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SP7. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SP7 antibody (ABIN2777381)

Milona, Gough, Edgar: "Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells." in: BMC genomics, Vol. 4, pp. 43, (2004) (PubMed).

Target Details for SP7

Target: SP7 (Sp7 Transcription Factor (SP7))

Alternative Name: SP7 (SP7 Products)

Synonyms: BBBG1 antibody, FXY antibody, GBBB1 antibody, MIDIN antibody, OGS1 antibody, OS antibody, OSX antibody, RNF59 antibody, TRIM18 antibody, XPRF antibody, ZNFXY antibody, OI11 antibody, OI12 antibody, osterix antibody, Osx antibody, osx antibody, SP7 antibody, sp7 antibody, 6430578P22Rik antibody, C22 antibody, midline 1 antibody, Sp7 transcription factor antibody, uncharacterized LOC100063836 antibody, Sp7 transcription factor L homeolog antibody, Sp7 transcription factor 7 antibody, MID1 antibody, SP7 antibody, Sp7 antibody, sp7 antibody, LOC100063836 antibody, sp7.L antibody

Background: SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation.
Alias Symbols: OSX, OI11, OI12, osterix
Protein Interaction Partner: UBC,
Protein Size: 431

Molecular Weight: 45 kDa

Gene ID: 121340

NCBI Accession: NM_152860, NP_690599

UniProt: Q8TDD2