AEBP1 antibody (N-Term)

Catalog No. ABIN2777370

Product Details anti-AEBP1 Antibody

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VPPEKTKDKG KKGKKDKGPK VPKESLEGSP RPPKKGKEKP PKATKKPKEK

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AEBP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AEBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AEBP1 antibody (ABIN2777370)

Kim, Gieske, Trudgen, Hudgins-Spivey, Kim, Krust, Chambon, Jeong, Blalock, Ko: "Identification of estradiol/ER?-regulated genes in the mouse pituitary." in: The Journal of endocrinology, Vol. 210, Issue 3, pp. 309-21, (2011) (PubMed).

Target Details for AEBP1

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Alternative Name: AEBP1 (AEBP1 Products)

Synonyms: ACLP antibody, AE binding protein 1 antibody, Closa_4071 antibody, AEBP1 antibody, Aebp1 antibody

Background: The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
Alias Symbols: ACLP
Protein Interaction Partner: GRB2, TCF3,
Protein Size: 1158

Molecular Weight: 131 kDa

Gene ID: 165

NCBI Accession: NM_001129, NP_001120

UniProt: Q14113