FOXP4 antibody (Middle Region)

Catalog No. ABIN2777345

Product Details anti-FOXP4 Antibody

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRLSPPQYSH QVQVKEEPAE AEEDRQPGPP LGAPNPSASG PPEDRDLEEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against FOXP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 680 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXP4 antibody (ABIN2777345)

Tuovinen, Kekäläinen, Rossi, Puntila, Arstila: "Cutting edge: human CD4-CD8- thymocytes express FOXP3 in the absence of a TCR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3651-4, (2008) (PubMed).

Target Details for FOXP4

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Alternative Name: FOXP4 (FOXP4 Products)

Synonyms: FOXP4 antibody, hfkhla antibody, FKHLA antibody, foxp4a antibody, foxp4b antibody, hFKHLA antibody, 1200010K03Rik antibody, 2310007G05Rik antibody, mFKHLA antibody, forkhead box P4 antibody, forkhead box P4 S homeolog antibody, FOXP4 antibody, foxp4 antibody, foxp4.S antibody, Foxp4 antibody

Background: FOXP4 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. FOXP4 may play a role in the development of tumors of the kidney and larynx. This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Alias Symbols: FLJ40908, FLJ44184, hFKHLA
Protein Interaction Partner: SOX2, MKI67, SUMO2, UBC, FOXP1, FOXP4, FOXP2,
Protein Size: 680

Molecular Weight: 73 kDa

Gene ID: 116113

NCBI Accession: NM_138457, NP_612466

UniProt: Q8IW55