TSFM antibody (Middle Region)

Catalog No. ABIN2777309

Product Details anti-TSFM Antibody

Target: TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSFM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTMMHCQTLK DQPSAYSKGF LNSSELSGLP AGPDREGSLK DQLALAIGKL

Predicted Reactivity: Cow: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TSFM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSFM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 346 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSFM

Target: TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))

Alternative Name: TSFM (TSFM Products)

Synonyms: EF-Ts antibody, EF-TsMt antibody, EFTS antibody, zgc:158429 antibody, EFTSMT antibody, 2310050B20Rik antibody, 9430024O13Rik antibody, EF-TS antibody, EF-Tsmt antibody, 2A3-2 antibody, Elongation factor Ts, mitochondrial antibody, Ts translation elongation factor, mitochondrial antibody, Ts translation elongation factor, mitochondrial L homeolog antibody, pco103788 antibody, tsfm antibody, tsfm.L antibody, TSFM antibody, Tsfm antibody

Background: The TSFM protein is a mitochondrial translation elongation factor. Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes.Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes. The TSFM gene encodes a mitochondrial translation elongation factor (Smeitink et al., 2006 [PubMed 17033963]).[supplied by OMIM].
Alias Symbols: COXPD3, EF-TS, EF-Tsmt, EFTS, EFTSMT
Protein Interaction Partner: UBC, SUMO2, LIG4, C1QBP, MRRF, ACOT13, CDV3, MTRNR2L1,
Protein Size: 346

Molecular Weight: 38 kDa

Gene ID: 10102

NCBI Accession: NM_005726, NP_005717

UniProt: P43897