Msx2/Hox8 antibody (N-Term)

Catalog No. ABIN2777276

Product Details anti-Msx2/Hox8 Antibody

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Msx2/Hox8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 91%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 267 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Msx2/Hox8

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Alternative Name: MSX2 (Msx2 Products)

Synonyms: CRS2 antibody, FPP antibody, HOX8 antibody, MSH antibody, PFM antibody, PFM1 antibody, BB122635 antibody, Hox-8 antibody, Hox8 antibody, Hox8.1 antibody, HOX-8 antibody, Msx-2 antibody, msh homeobox 2 antibody, MSX2 antibody, Msx2 antibody

Background: MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRS2, FPP, HOX8, MSH, PFM, PFM1
Protein Interaction Partner: ATXN1, PIAS2, UBC, XRCC5, XRCC6, ZDHHC2, TLE2, TLE1, PPARG, POU2AF1, NR3C1, POLR3D, SPEN, ZBTB17, RUNX2, DLX5, MAGED1, GTF2F2, GTF2F1, MSX1, DLX2, MSX2, CEBPA, PITX2,
Protein Size: 267

Molecular Weight: 29 kDa

Gene ID: 4488

NCBI Accession: NM_002449, NP_002440

UniProt: P35548