FOSL2 antibody (Middle Region)

Catalog No. ABIN2777246

Product Details anti-FOSL2 Antibody

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PMRSGGGSVG AVVVKQEPLE EDSPSSSSAG LDKAQRSVIK PISIAGGFY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against FOSL2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOSL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FOSL2 (FOSL2 Products)

Synonyms: FOSL2 antibody, FRA2 antibody, Fra-2 antibody, Fra2 antibody, fra2 antibody, wu:fl17h04 antibody, xx:fl17h04 antibody, zgc:158347 antibody, PLB1 antibody, fra-2 antibody, FOS like 2, AP-1 transcription factor subunit antibody, fos-like antigen 2 antibody, FOSL2 antibody, Fosl2 antibody, fosl2 antibody

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2, which encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: FRA2
Protein Interaction Partner: GMCL1, GOPC, LUZP4, CREB5, DNAJA3, TRAF1, FHL3, DDIT3, JUNB, UBC, SRA1, ATF1, EP300, SUMO2, JUND, JUN,
Protein Size: 326

Molecular Weight: 35 kDa

Gene ID: 2355

NCBI Accession: NM_005253, NP_005244

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism