DR1 antibody (Middle Region)
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- Target See all DR1 Antibodies
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KKTISPEHVI QALESLGFGS YISEVKEVLQ ECKTVALKRR KASSRLENLG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Dr1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product DR1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 176 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Alternative Name
- Dr1 (DR1 Products)
- Synonyms
- BG:DS00929.3 antibody, CG4185 antibody, Dmel\\CG4185 antibody, Dr1 antibody, NC2 beta antibody, Nc2b antibody, dDr1 antibody, dNC2 antibody, wu:fj15f04 antibody, zgc:152914 antibody, 1700121L09Rik antibody, Dr1l antibody, NC2 antibody, NC2beta antibody, NC2-BETA antibody, Negative Cofactor 2beta antibody, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN antibody, TATA-binding protein-associated phosphoprotein antibody, putative tata-binding protein-associated phosphoprotein antibody, down-regulator of transcription 1 antibody, down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody, NC2beta antibody, ECU11_0730 antibody, EDI_229030 antibody, PTRG_08168 antibody, Smp_160150 antibody, EBI_26279 antibody, EBI_23074 antibody, VDBG_02216 antibody, dr1 antibody, Dr1 antibody, DR1 antibody
- Background
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The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Dr1 can bind to DNA on its own. It is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Alias Symbols: 1700121L09Rik, Dr1l, NC2, NC2beta
Protein Interaction Partner: Csrp2bp,
Protein Size: 176 - Molecular Weight
- 19 kDa
- Gene ID
- 13486
- NCBI Accession
- NM_026106, NP_080382
- UniProt
- Q91WV0
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