TFCP2 antibody (N-Term)

Catalog No. ABIN2777203

Product Details anti-TFCP2 Antibody

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFCP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YSMSDVLALP IFKQEESSLP PDNENKILPF QYVLCAATSP AVKLHDETLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TFCP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFCP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 502 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFCP2

Target: TFCP2 (Transcription Factor CP2 (TFCP2))

Alternative Name: TFCP2 (TFCP2 Products)

Synonyms: cp2 antibody, lsf antibody, sef antibody, lbp-1c antibody, tfcp2c antibody, MGC75945 antibody, TFCP2 antibody, lbp1c antibody, lsf1d antibody, TCFCP2 antibody, LBP1C antibody, LSF antibody, LSF1D antibody, SEF antibody, TFCP2C antibody, CP-2 antibody, CP2 antibody, D230015P20Rik antibody, LBP-1c antibody, LBP-1d antibody, LBP1 antibody, Tcfcp2 antibody, UBP-1 antibody, transcription factor CP2 antibody, transcription factor CP2 L homeolog antibody, tfcp2 antibody, TFCP2 antibody, tfcp2.L antibody, Tfcp2 antibody

Background: TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Alias Symbols: CP2, LBP-1C, LSF, SEF, TFCP2C, LBP1C, LSF1D
Protein Interaction Partner: E2F8, NPEPL1, CDC73, MRPL11, KIAA1598, CBX8, TDRD1, CCDC94, ASAP3, C19orf73, FANCL, ZCCHC10, FAM64A, DNAJC27, TRAPPC12, POLL, TSPAN12, PLCB1, STMN2, MORF4L1, FARS2, EIF5B, PITPNM1, PPIG, GPANK1, BAG6, SUMO1, TCEA2, SDCBP, RBMS1, PSMD5, PPP3R2, PHF1, MRPL4
Protein Size: 502

Molecular Weight: 57 kDa

Gene ID: 7024

NCBI Accession: NM_005653, NP_005644

UniProt: Q12800