PR (N-Term) antibody
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- Target
- PR
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LPRGLSPARQ LLLPASESPH WSGAPVKPSP QAAAVEVEEE DGSESEESAG
- Predicted Reactivity
- Human: 100%, Rabbit: 91%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against PR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human PGR
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PR
- Synonyms
- SPC antibody, proline rich protein gene cluster antibody, PR@ antibody
- Background
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This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Alias Symbols: PR, NR3C3
Protein Size: 690 - Molecular Weight
- 75 kDa
- Gene ID
- 5241
- NCBI Accession
- NM_000926, NP_000917
- UniProt
- P06401
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