RDH16 antibody (Middle Region)

Catalog No. ABIN2777161

Product Details anti-RDH16 Antibody

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKERFLKSFL EIWDRSSPEV KEAYGEKFVA DYKKSAEQME QKCTQDLSLV

Predicted Reactivity: Dog: 85%, Horse: 79%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against RDH16. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RDH16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 317 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RDH16

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Alternative Name: RDH16 (RDH16 Products)

Synonyms: MGC68820 antibody, CRAD antibody, CRAD1 antibody, Rdh6 antibody, RODH-4 antibody, SDR9C8 antibody, Rdh2 antibody, RoDHII antibody, retinol dehydrogenase 16 (all-trans) L homeolog antibody, retinol dehydrogenase 16 (all-trans) antibody, retinol dehydrogenase 16 antibody, rdh16.L antibody, RDH16 antibody, rdh16 antibody, Rdh16 antibody

Background: RDH16 is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol than with free retinol. It also oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. RDH16 can also catalyze the reverse reaction.
Alias Symbols: RODH-4, SDR9C8
Protein Size: 317

Molecular Weight: 36 kDa

Gene ID: 8608

NCBI Accession: NM_003708, NP_003699

UniProt: O75452

Pathways: Steroid Hormone Biosynthesis