UPP1 antibody (N-Term)

Catalog No. ABIN2777156

Product Details anti-UPP1 Antibody

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Horse, Rat, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AATGANAEKA ESHNDCPVRL LNPNIAKMKE DILYHFNLTT SRHNFPALFG

Predicted Reactivity: Cow: 85%, Guinea Pig: 75%, Horse: 83%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against UPP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UPP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 310 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-UPP1 antibody (ABIN2777156)

Temmink, de Bruin, Laan, Turksma, Cricca, Masterson, Noordhuis, Peters: "The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells." in: The international journal of biochemistry & cell biology, Vol. 38, Issue 10, pp. 1759-65, (2006) (PubMed).

Target Details for UPP1

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Alternative Name: UPP1 (UPP1 Products)

Synonyms: upp1 antibody, UDRPASE antibody, UP antibody, UPASE antibody, UPP antibody, im:6911242 antibody, zgc:110755 antibody, AI325217 antibody, UPase antibody, UdRPase antibody, Up antibody, Upp antibody, uridine phosphorylase 1 antibody, uridine phosphorylase antibody, upp1 antibody, NP_RS08675 antibody, Tsp_02326 antibody, UPP1 antibody, Upp1 antibody

Background: UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Alias Symbols: UDRPASE, UP, UPASE, UPP
Protein Interaction Partner: CTDP1, YRDC, WDR45B, WBP2, UCK2, UBE2D1, MPST, UBC, EBNA-LP, VIM,
Protein Size: 310

Molecular Weight: 34 kDa

Gene ID: 7378

NCBI Accession: NM_003364, NP_003355

UniProt: Q16831

Pathways: Ribonucleoside Biosynthetic Process