MMP3 antibody (Middle Region)
-
- Target See all MMP3 Antibodies
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Rabbit, Pig, Cow, Dog, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MMP3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- AEDFPGIDSK IDAVFEEFGF FYFFTGSSQL EFDPNAKKVT HTLKSNSWLN
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against MMP3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MMP3
- Top Product
- Discover our top product MMP3 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 477 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease." in: Alcoholism, clinical and experimental research, Vol. 32, Issue 6, pp. 959-65, (2008) (PubMed).
: "
-
No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease." in: Alcoholism, clinical and experimental research, Vol. 32, Issue 6, pp. 959-65, (2008) (PubMed).
-
- Target
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- Alternative Name
- MMP3 (MMP3 Products)
- Synonyms
- CHDS6 antibody, MMP-3 antibody, SL-1 antibody, STMY antibody, STMY1 antibody, STR1 antibody, SLN-1 antibody, SLN1 antibody, STR-1 antibody, Stmy1 antibody, Str1 antibody, MMP10 antibody, chds6 antibody, mmp-3 antibody, mmp13 antibody, mmp3 antibody, sl-1 antibody, stmy antibody, stmy1 antibody, str1 antibody, matrix metallopeptidase 3 antibody, matrix metallopeptidase 3 (stromelysin 1, progelatinase) antibody, matrix metallopeptidase 3 L homeolog antibody, MMP3 antibody, Mmp3 antibody, mmp3.L antibody
- Background
-
MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6
Protein Interaction Partner: MEOX2, SPOCK3, SPOCK1, TNFSF11, CCL8, CCL13, BCAN, TIMP1, TIMP3, MMP3, SERPINE1, PLG, SPP1, CCL7, CCL2, ACAN, IGFBP3, DCN, HAPLN1,
Protein Size: 477 - Molecular Weight
- 43 kDa
- Gene ID
- 4314
- NCBI Accession
- NM_002422, NP_002413
- UniProt
- P08254
-