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BDNF antibody (N-Term)
BDNF
Reactivity: Human, Rat, Mouse, Pig, Rabbit, Dog, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BDNF Antibody
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Target
See all BDNF Antibodies
BDNF
(Brain-Derived Neurotrophic Factor (BDNF))
Binding Specificity
All epitopes for BDNF antibodies
N-Term
Reactivity
All reactivities for BDNF antibodies
Human, Rat, Mouse, Pig, Rabbit, Dog, Zebrafish (Danio rerio)
Host
All hosts for BDNF antibodies
Rabbit
Clonality
All clonalities for BDNF antibodies
Polyclonal
Conjugate
All conjugates for BDNF antibodies
This BDNF antibody is un-conjugated
Application
All applications for BDNF antibodies
Western Blotting (WB)
Sequence
EELLDEDQKV RPNEENNKDA DLYTSRVMLS SQVPLEPPLL FLLEEYKNYL
Predicted Reactivity
Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human BDNF
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
References for anti-BDNF antibody (ABIN2777092)
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Galindo, Soslow, Brinkmeyer-Langford, Gupte, Smith, Sengsayadeth, Sawyer, Benson, Kornegay, Markham : "Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy. " in: Pediatric research , Vol. 79 , Issue 4 , pp. 629-36 , (2016 ) (PubMed ).
Target Details for BDNF
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Target
BDNF
(Brain-Derived Neurotrophic Factor (BDNF))
Alternative Name
BDNF (BDNF Products )
Synonyms
ANON2 antibody, BULN2 antibody, bdnf-A antibody, BDNF antibody, bdnf antibody, brain derived neurotrophic factor antibody, brain-derived neurotrophic factor antibody, brain-derived neurotrophic factor L homeolog antibody, brain-derived neurotrophic factor S homeolog antibody, BDNF antibody, Bdnf antibody, bdnf antibody, bdnf.L antibody, bdnf.S antibody
Background
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. Protein Interaction Partner: UBC, AGO3, INPP5K, F11R, JUNB, APP, ELAVL1, Ntrk2, CADPS2, MBTPS1, SORT1, NOS3, NTF4, NTF3, ESR1, NCAM1, CPE, BDNF, Protein Size: 329
Molecular Weight
36 kDa
Gene ID
627
Pathways
RTK Signaling , Synaptic Membrane , Feeding Behaviour , Dicarboxylic Acid Transport , Regulation of long-term Neuronal Synaptic Plasticity
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