SIGLEC6 antibody (N-Term)

Catalog No. ABIN2777066

Product Details anti-SIGLEC6 Antibody

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Binding Specificity: N-Term

Reactivity: Human, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL

Predicted Reactivity: Cow: 79%, Horse: 86%, Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against SIGLEC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIGLEC6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIGLEC6

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Alternative Name: SIGLEC6 (SIGLEC6 Products)

Synonyms: SIGLEC6 antibody, CD327 antibody, CD33L antibody, CD33L1 antibody, CD33L2 antibody, CDW327 antibody, OBBP1 antibody, sialic acid binding Ig like lectin 6 antibody, SIGLEC6 antibody

Background: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Alias Symbols: CD33L, CD33L1, CDw327, OBBP1, SIGLEC-6, CD327, CD33L2, CDW327
Protein Interaction Partner: TCF4, FHL2, LEP,
Protein Size: 442

Molecular Weight: 47 kDa

Gene ID: 946

NCBI Accession: NM_001245, NP_001236

UniProt: O43699