RPAIN antibody (C-Term)

Catalog No. ABIN2777047

Product Details anti-RPAIN Antibody

Target: RPAIN (RPA Interacting Protein (RPAIN))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPAIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VVCQCGLSIP SHSSELTEQK LRACLEGSIN EHSAHCPHTP EFSVTGGTEE

Predicted Reactivity: Cow: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RPAIN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RPAIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 219 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPAIN

Target: RPAIN (RPA Interacting Protein (RPAIN))

Alternative Name: RPAIN (RPAIN Products)

Synonyms: HRIP antibody, RIP antibody, 2400006N03Rik antibody, RP23-83I13.5 antibody, Rip antibody, RGD1308492 antibody, RPAIN antibody, MGC153251 antibody, rpain antibody, xripalpha antibody, rip-B antibody, RPA interacting protein antibody, RPA interacting protein S homeolog antibody, RPA interacting protein L homeolog antibody, RPAIN antibody, Rpain antibody, rpain antibody, rpain.S antibody, rpain.L antibody

Background: RPAIN mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.
Alias Symbols: FLJ25625, FLJ30490, FLJ42429, HRIP, MGC4189, RIP
Protein Interaction Partner: CDCA5, GSTA1, CYP17A1, ADH6, UBC,
Protein Size: 219

Molecular Weight: 25 kDa

Gene ID: 84268

NCBI Accession: NM_001033002, NP_001028174

UniProt: Q86UA6

Pathways: Protein targeting to Nucleus