LSS antibody (Middle Region)

Catalog No. ABIN2777021

Product Details anti-LSS Antibody

Target: LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KCPHVTEHIP RERLCDAVAV LLNMRNPDGG FATYETKRGG HLLELLNPSE

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LSS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LSS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 732 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LSS

Target: LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))

Alternative Name: LSS (LSS Products)

Synonyms: OSC antibody, 2810025N20Rik antibody, BC029082 antibody, D10Ertd116e antibody, Osc antibody, xlss antibody, Tb07.27E10.490 antibody, NCU01119.1 antibody, lanosterol synthase antibody, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) antibody, putative lanosterol synthase antibody, Lanosterol synthase, putative antibody, LSS antibody, Lss antibody, lss antibody, CND02520 antibody, Tc00.1047053506825.170 antibody, Tc00.1047053508175.70 antibody, Tb927.7.5230 antibody, NCU01119 antibody, LMJF_06_0650 antibody, CGB_D5080W antibody, LOC100636608 antibody

Background: LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: OSC
Protein Interaction Partner: UBC, SUMO1, NEDD8, ATP4A, NR4A1,
Protein Size: 732

Molecular Weight: 83 kDa

Gene ID: 4047

NCBI Accession: NM_002340, NP_002331

UniProt: P48449