PTGS1 antibody (N-Term)
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- Target See all PTGS1 Antibodies
- PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Sheep, Cow, Horse, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTGS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LDRYQCDCTR TGYSGPNCTI PGLWTWLRNS LRPSPSFTHF LLTHGRWFWE
- Predicted Reactivity
- Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 93%, Sheep: 79%
- Characteristics
- This is a rabbit polyclonal antibody against PTGS1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PTGS1
- Top Product
- Discover our top product PTGS1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 599 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
- Alternative Name
- PTGS1 (PTGS1 Products)
- Synonyms
- COX-1 antibody, cox-1 antibody, PTGS1 antibody, Ptgs1 antibody, COX1 antibody, Cox-1 antibody, Cox-3 antibody, PGHS-1 antibody, PHS 1 antibody, Pghs1 antibody, Cox1 antibody, Cox3 antibody, cox1 antibody, zCOX-1 antibody, COX3 antibody, PCOX1 antibody, PES-1 antibody, PGG/HS antibody, PGHS1 antibody, PHS1 antibody, PTGHS antibody, COX-3 antibody, prostaglandin-endoperoxide synthase 1 antibody, cyclooxygenase-1 antibody, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody, prostaglandin-endoperoxide synthase 1 S homeolog antibody, PTGS1 antibody, cox-1 antibody, Ptgs1 antibody, ptgs1 antibody, ptgs1.S antibody
- Background
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Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Alias Symbols: COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Protein Interaction Partner: FBXO6, PTGS2, NCL, CAV2, CAV1, PTGIS, Dlg4, PTGS1, NUCB1,
Protein Size: 599 - Molecular Weight
- 69 kDa
- Gene ID
- 5742
- NCBI Accession
- NM_000962, NP_000953
- UniProt
- P23219
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