OXT antibody (N-Term)
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- Target See all OXT Antibodies
- OXT (Oxytocin, Prepropeptide (OXT))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OXT antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA
- Predicted Reactivity
- Cow: 85%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Sheep: 85%
- Characteristics
- This is a rabbit polyclonal antibody against OXT. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product OXT Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 125 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- OXT (Oxytocin, Prepropeptide (OXT))
- Alternative Name
- OXT (OXT Products)
- Synonyms
- OT antibody, OT-NPI antibody, OXT-NPI antibody, Oxy antibody, OTNPI antibody, NEURL1 antibody, RNF67 antibody, bA416N2.1 antibody, neu antibody, neu-1 antibody, Ocytocin antibody, Oxytocin antibody, oxytocin/neurophysin I prepropeptide antibody, oxytocin antibody, oxytocin/neurophysin 1 prepropeptide antibody, neuralized E3 ubiquitin protein ligase 1 antibody, vasopressin-neurophysin 2 antibody, OXT antibody, Oxt antibody, NEURL1 antibody, LOC100066842 antibody
- Background
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There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Alias Symbols: MGC126890, MGC126892, OT, OT-NPI
Protein Interaction Partner: TXNDC17, ESR2, PREP, OXTR, KMT2A,
Protein Size: 125 - Molecular Weight
- 9 kDa
- Gene ID
- 5020
- NCBI Accession
- NM_000915, NP_000906
- UniProt
- P01178
- Pathways
- Myometrial Relaxation and Contraction, Feeding Behaviour
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