GHRHR antibody (N-Term)
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- Target See all GHRHR Antibodies
- GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Pig, Cow, Sheep, Dog, Rabbit, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GHRHR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VTLPCPDFFS HFSSESGAVK RDCTITGWSE PFPPYPVACP VPLELLAEEE
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 93%, Sheep: 79%
- Characteristics
- This is a rabbit polyclonal antibody against GHRHR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GHRHR
- Top Product
- Discover our top product GHRHR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 423 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))
- Alternative Name
- GHRHR (GHRHR Products)
- Synonyms
- GHRFR antibody, GRFR antibody, IGHD1B antibody, Ghrfr antibody, lit antibody, little antibody, GHRHREC antibody, GHRH-R antibody, growth hormone releasing hormone receptor antibody, GHRHR antibody, Ghrhr antibody
- Background
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GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.This This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.
Alias Symbols: GHRFR, GHRHRpsv, GRFR, IGHD1B
Protein Interaction Partner: GHRH, GHRL, MLNR,
Protein Size: 423 - Molecular Weight
- 47 kDa
- Gene ID
- 2692
- NCBI Accession
- NM_000823, NP_000814
- UniProt
- Q02643
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process
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