C8G antibody (N-Term)

Catalog No. ABIN2776987

Product Details anti-C8G Antibody

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Pig, Rabbit, Dog, Rat, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8G antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VGSACRFLQE QGHRAEATTL HVAPQGTAMA VSTFRKLDGI CWQVRQLYGD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C8G. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8G

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C8G

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: C8G (C8G Products)

Synonyms: C8C antibody, complement C8 gamma chain antibody, complement component 8, gamma polypeptide antibody, C8G antibody, C8g antibody

Background: The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Alias Symbols: C8C
Protein Interaction Partner: C8A,
Protein Size: 202

Molecular Weight: 22 kDa

Gene ID: 733

NCBI Accession: NM_000606, NP_000597

UniProt: P07360

Pathways: Complement System