GSTM1 antibody (C-Term)

Catalog No. ABIN2776985

Product Details anti-GSTM1 Antibody

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PEKLKLYSEF LGKRPWFAGN KGLEKISAYM KSSRFLPRPV FSKMAVWGNK

Predicted Reactivity: Cow: 86%, Dog: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GSTM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSTM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 181 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Alternative Name: GSTM1 (GSTM1 Products)

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.
Alias Symbols: GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MGC26563, MU, MU-1
Protein Interaction Partner: GSTM3, UBC, IQCB1, MAP3K5, GSTM2, GSTM1,
Protein Size: 181

Molecular Weight: 21 kDa

Gene ID: 2944

NCBI Accession: NM_146421, NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity