Keratin 2 antibody (Middle Region)
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- Target See all Keratin 2 (KRT2) Antibodies
- Keratin 2 (KRT2)
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Keratin 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EVKAQYEEIA QRSKEEAEAL YHSKYEELQV TVGRHGDSLK EIKIEISELN
- Predicted Reactivity
- Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 81%
- Characteristics
- This is a rabbit polyclonal antibody against KRT2A. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KRT2A
- Top Product
- Discover our top product KRT2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 639 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Keratin 2 (KRT2)
- Alternative Name
- KRT2A (KRT2 Products)
- Synonyms
- KRT2 antibody, krt2a antibody, CK-2e antibody, K2e antibody, KRT2A antibody, KRT2E antibody, KRTE antibody, BB005427 antibody, Krt2-17 antibody, Krt2-2 antibody, Krt2e antibody, Kb2 antibody, K2E antibody, keratin 2 antibody, KRT2 antibody, Krt2 antibody
- Background
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KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: KRT2E, KRTE, K2e, CK-2e, KRT2A
Protein Interaction Partner: KRT40, KRT38, KRT31, KRT19, KRT13, Fbxl16, LGR4, EED, ADRB2, PAN2, Nphp4, IQCB1, VCAM1, UBC, FN1, EIF4A3, MAGOH, KRT10, KRT1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5,
Protein Size: 639 - Molecular Weight
- 70 kDa
- Gene ID
- 3849
- NCBI Accession
- NM_000423, NP_000414
- UniProt
- P35908
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