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Keratin 2 antibody (Middle Region)

KRT2 Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776963
  • Target See all Keratin 2 (KRT2) Antibodies
    Keratin 2 (KRT2)
    Binding Specificity
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Rat, Mouse, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse
    Host
    • 56
    • 4
    • 2
    Rabbit
    Clonality
    • 49
    • 13
    Polyclonal
    Conjugate
    • 27
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 2 antibody is un-conjugated
    Application
    • 45
    • 20
    • 15
    • 14
    • 14
    • 10
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EVKAQYEEIA QRSKEEAEAL YHSKYEELQV TVGRHGDSLK EIKIEISELN
    Predicted Reactivity
    Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 81%
    Characteristics
    This is a rabbit polyclonal antibody against KRT2A. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human KRT2A
    Top Product
    Discover our top product KRT2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 639 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Keratin 2 (KRT2)
    Alternative Name
    KRT2A (KRT2 Products)
    Synonyms
    KRT2 antibody, krt2a antibody, CK-2e antibody, K2e antibody, KRT2A antibody, KRT2E antibody, KRTE antibody, BB005427 antibody, Krt2-17 antibody, Krt2-2 antibody, Krt2e antibody, Kb2 antibody, K2E antibody, keratin 2 antibody, KRT2 antibody, Krt2 antibody
    Background
    KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
    Alias Symbols: KRT2E, KRTE, K2e, CK-2e, KRT2A
    Protein Interaction Partner: KRT40, KRT38, KRT31, KRT19, KRT13, Fbxl16, LGR4, EED, ADRB2, PAN2, Nphp4, IQCB1, VCAM1, UBC, FN1, EIF4A3, MAGOH, KRT10, KRT1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5,
    Protein Size: 639
    Molecular Weight
    70 kDa
    Gene ID
    3849
    NCBI Accession
    NM_000423, NP_000414
    UniProt
    P35908
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