KRT17 antibody (C-Term)

Catalog No. ABIN2776962

Product Details anti-KRT17 Antibody

Target: KRT17 (Keratin 17 (KRT17))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog, Rabbit, Sheep, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IATYRRLLEG EDAHLTQYKK EPVTTRQVRT IVEEVQDGKV ISSREQVHQT

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against KRT17. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: KRT17 (KRT17 Products)

Synonyms: K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody

Background: KRT17 is type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in its gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.KRT17 encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Alias Symbols: K17, PC, PC2, PCHC1
Protein Interaction Partner: TRIM69, UBC, MDM2, IGF2BP3, IKBKG, PA2G4, CRYZ, KDM1A, GRB2, Iqcb1, Nphp1, Invs, CALR, ILF3, UBASH3B, SHC1, PIK3R2, INPPL1, EPS15, CRK, AP2M1, CBL, COPS5, SUMO2, YWHAQ, APC, USP1, UCHL1, CCDC85B, KRT7, KRT6A, EGFR, KRT72, KRT8,
Protein Size: 432

Molecular Weight: 48 kDa

Gene ID: 3872

NCBI Accession: NM_000422, NP_000413

UniProt: Q04695