STS antibody (C-Term)

Catalog No. ABIN2776951

Product Details anti-STS Antibody

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLFDISKDPR ERNPLTPASE PRFYEILKVM QEAADRHTQT LPEVPDQFSW

Predicted Reactivity: Cow: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against STS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 583 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-STS antibody (ABIN2776951)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: STS (STS Products)

Synonyms: ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, abcg2 antibody, ArsC antibody, Sts antibody, si:ch211-271l9.1 antibody, steroid sulfatase antibody, breast cancer resistance protein antibody, Steryl-sulfatase antibody, steryl-sulfatase antibody, steroid sulfatase (microsomal), isozyme S antibody, STS antibody, abcg2 antibody, Sts antibody, Plav_0360 antibody, Psta_3963 antibody, Runsl_5106 antibody, LOC100712701 antibody, sts antibody

Background: STS catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in its gene are known to cause X-linked ichthyosisThe protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
Alias Symbols: ARSC, ARSC1, ASC, ES, SSDD, XLI
Protein Size: 583

Molecular Weight: 64 kDa

Gene ID: 412

NCBI Accession: NM_000351, NP_000342

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis