GAMT antibody (N-Term)

Catalog No. ABIN2776937

Product Details anti-GAMT Antibody

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSAPSATPIF APGENCSPAW GAAPAAYDAA DTHLRILGKP VMERWETPYM

Predicted Reactivity: Cow: 92%, Guinea Pig: 85%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GAMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 236 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT (GAMT Products)

Synonyms: gamt antibody, zgc:123136 antibody, CCDS2 antibody, PIG2 antibody, TP53I2 antibody, AA571402 antibody, Spintz1 antibody, MGC75698 antibody, GAMT antibody, GMT antibody, guanidinoacetate N-methyltransferase L homeolog antibody, guanidinoacetate N-methyltransferase S homeolog antibody, guanidinoacetate N-methyltransferase antibody, guanidinoacetate methyltransferase antibody, gamt.L antibody, gamt.S antibody, gamt antibody, GAMT antibody, Gamt antibody

Background: GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PIG2, TP53I2
Protein Interaction Partner: FOS, CSNK2B, UBC, TERF2IP, POT1, TERF1,
Protein Size: 236

Molecular Weight: 26 kDa

Gene ID: 2593

NCBI Accession: NM_000156, NP_000147

UniProt: Q14353