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ALAD antibody (N-Term)

ALAD Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776920
  • Target See all ALAD Antibodies
    ALAD (Aminolevulinate Dehydratase (ALAD))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 23
    • 19
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae
    Host
    • 35
    • 5
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALAD antibody is un-conjugated
    Application
    • 38
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    QPQSVLHSGY FHPLLRAWQT ATTTLNASNL IYPIFVTDVP DDIQPITSLP
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 77%, Zebrafish: 83%
    Characteristics
    This is a rabbit polyclonal antibody against ALAD. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ALAD
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    Discover our top product ALAD Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 339 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ALAD (Aminolevulinate Dehydratase (ALAD))
    Alternative Name
    ALAD (ALAD Products)
    Synonyms
    DDBDRAFT_0190269 antibody, DDBDRAFT_0231415 antibody, DDB_0190269 antibody, DDB_0231415 antibody, ALAD antibody, ncf antibody, ALADH antibody, PBGS antibody, ALADR antibody, aminolevulinatedelta-dehydratase antibody, zgc:110219 antibody, Lv antibody, delta-aminolevulinate dehydratase antibody, aminolevulinate dehydratase antibody, delta-aminolevulinic acid dehydratase antibody, Delta-aminolevulinic acid dehydratase antibody, aminolevulinate dehydratase L homeolog antibody, aminolevulinate, delta-, dehydratase antibody, hemB antibody, ALAD antibody, PBGS antibody, STY0404 antibody, SAS1597 antibody, SACI_RS03725 antibody, PAAG_00299 antibody, VDBG_00315 antibody, HPPC_00830 antibody, MGYG_01952 antibody, hem2 antibody, alad.L antibody, Alad antibody, alad antibody
    Background
    The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ALADH, MGC5057, PBGS
    Protein Interaction Partner: C14orf142, P3H1, RPRD1B, PPME1, LAP3, DBNL, HSPBP1, GPN1, WDR4, ACTR2, TOM1L1, ZPR1, OGT, SURF2, LPP, AGFG1, UBD, UBC, ALAD,
    Protein Size: 339
    Molecular Weight
    37 kDa
    Gene ID
    210
    NCBI Accession
    NM_000031, NP_000022
    UniProt
    P13716
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