VSIG4 antibody (N-Term)

Catalog No. ABIN310179

Product Details anti-VSIG4 Antibody

Target: VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))

Binding Specificity: N-Term

Reactivity: Human, Rat, Pig, Cow, Horse, Mouse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSIG4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VPGDVSLQLS TLEMDDRSHY TCEVTWQTPD GNQVVRDKIT ELRVQKLSVS

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 92%, Horse: 91%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 82%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against VSIG4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VSIG4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VSIG4

Target: VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))

Alternative Name: VSIG4 (VSIG4 Products)

Background: T cell activation by APCs is positively and negatively regulated by members of the B7 family. VSIG4 is a strong negative regulator of murine and human T cell proliferation and IL-2 production.
Alias Symbols: Z39IG, CRIg
Protein Interaction Partner: PDK2, nef, APP, C3,
Protein Size: 399

Molecular Weight: 44 kDa

Gene ID: 11326

NCBI Accession: NM_007268, NP_009199

UniProt: Q9Y279