FTCD antibody (Middle Region)

Catalog No. ABIN2776888

Product Details anti-FTCD Antibody

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTCD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KFLIAFNINL LGTKEQAHRI ALNLREQGRG KDQPGRLKKV QGIGWYLDEK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FTCD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FTCD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 549 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FTCD antibody (ABIN2776888)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for FTCD

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Alternative Name: FTCD (FTCD Products)

Synonyms: LCHC1 antibody, FTCD antibody, wu:fp37b11 antibody, zgc:63647 antibody, formimidoyltransferase cyclodeaminase antibody, formiminotransferase cyclodeaminase antibody, formiminotransferase-cyclodeaminase antibody, formimidoyltransferase cyclodeaminase L homeolog antibody, FTCD antibody, Ftcd antibody, ftcd antibody, DP2350 antibody, Cbei_0990 antibody, TRQ2_1223 antibody, GAU_0899 antibody, ftcd.L antibody

Background: FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.[supplied by OMIM].
Alias Symbols: LCHC1
Protein Interaction Partner: CCDC155, MED4, TNKS2, GRB14,
Protein Size: 549

Molecular Weight: 59 kDa

Gene ID: 10841

NCBI Accession: NM_006657, NP_006648

UniProt: O95954