MASP2 antibody (Middle Region)

Catalog No. ABIN2776886

Product Details anti-MASP2 Antibody

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MASP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YPQPYPKLSS CTYSIRLEDG FSVILDFVES FDVETHPEAQ CPYDSLKIQT

Predicted Reactivity: Cow: 100%, Guinea Pig: 79%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 92%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against Masp2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 685 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Alternative Name: Masp2 (MASP2 Products)

Synonyms: MAP19 antibody, MASP-2 antibody, MASP1P1 antibody, sMAP antibody, MAp19 antibody, mannan binding lectin serine peptidase 2 antibody, mannan-binding lectin serine peptidase 2 antibody, MASP2 antibody, Masp2 antibody

Background: Masp2 is a serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Alias Symbols: MASP-2, MAp19
Protein Size: 685

Molecular Weight: 75 kDa

Gene ID: 17175

NCBI Accession: NM_001003893, NP_001003893

UniProt: Q91WP0

Pathways: Complement System