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GPX3 antibody (N-Term)

GPX3 Reactivity: Human, Mouse, Rat, Pig, Dog, Cow, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776848
  • Target See all GPX3 Antibodies
    GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Pig, Dog, Cow, Guinea Pig
    Host
    • 35
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 39
    • 1
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPX3 antibody is un-conjugated
    Application
    • 40
    • 21
    • 18
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    DCHGGISGTI YEYGALTIDG EEYIPFKQYA GKYVLFVNVA SYUGLTGQYI
    Predicted Reactivity
    Cow: 100%, Dog: 83%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GPX3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GPX3
    Top Product
    Discover our top product GPX3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 226 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Maccarrone, Ditzen, Yassouridis, Rewerts, Uhr, Uhlen, Holsboer, Turck: "Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters." in: Journal of psychiatric research, Vol. 47, Issue 11, pp. 1572-80, (2013) (PubMed).

  • Target
    GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
    Alternative Name
    GPX3 (GPX3 Products)
    Synonyms
    GPX3 antibody, DKFZp469D1932 antibody, AA960521 antibody, EGPx antibody, GPx antibody, GSHPx-3 antibody, GSHPx-P antibody, GPx-3 antibody, GPx-P antibody, Gpxp antibody, glutathione peroxidase 3 antibody, gpx3 antibody, GPX3 antibody, Gpx3 antibody
    Background
    GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
    Alias Symbols: GPx-P, GSHPx-3, GSHPx-P
    Protein Interaction Partner: UBQLN1, GPX3,
    Protein Size: 226
    Molecular Weight
    25 kDa
    Gene ID
    2878
    NCBI Accession
    NM_002084, NP_002075
    UniProt
    P22352
    Pathways
    Thyroid Hormone Synthesis
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