SLC13A3 antibody (Middle Region)

Catalog No. ABIN2776815

Product Details anti-SLC13A3 Antibody

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Mouse, Rat, Rabbit, Cow, Horse, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC13A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GLSFRGWRKN KSEIRTNAED RARAVIREEY QNLGPIKFAE QAVFILFCMF

Predicted Reactivity: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 85%, Rabbit: 93%, Rat: 92%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SLC13A3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC13A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 555 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC13A3

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Alternative Name: SLC13A3 (SLC13A3 Products)

Synonyms: MGC108337 antibody, SLC13A3 antibody, zgc:77173 antibody, nadc3 antibody, sdct2 antibody, NADC3 antibody, SDCT2 antibody, NaDC-3 antibody, NaDC3 antibody, Nadc3 antibody, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 antibody, solute carrier family 13 member 3 antibody, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 L homeolog antibody, slc13a3 antibody, SLC13A3 antibody, slc13a3.L antibody, Slc13a3 antibody

Background: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
Alias Symbols: NADC3, SDCT2
Protein Size: 555

Molecular Weight: 61 kDa

Gene ID: 64849

NCBI Accession: NM_001011554, NP_001011554

UniProt: Q8WWT9

Pathways: Dicarboxylic Acid Transport