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SFTPB antibody (Middle Region)

SFTPB Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776796
  • Target See all SFTPB Antibodies
    SFTPB (Surfactant Protein B (SFTPB))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep
    Host
    • 40
    • 5
    Rabbit
    Clonality
    • 42
    • 3
    Polyclonal
    Conjugate
    • 25
    • 7
    • 5
    • 4
    • 2
    • 2
    This SFTPB antibody is un-conjugated
    Application
    • 41
    • 23
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PGALQARPGP HTQDLSEQQF PIPLPYCWLC RALIKRIQAM IPKGALAVAV
    Predicted Reactivity
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%, Sheep: 79%
    Characteristics
    This is a rabbit polyclonal antibody against SFTPB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SFTPB
    Top Product
    Discover our top product SFTPB Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 381 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SFTPB (Surfactant Protein B (SFTPB))
    Alternative Name
    SFTPB (SFTPB Products)
    Synonyms
    PSP-B antibody, SFTB3 antibody, SFTP3 antibody, SMDP1 antibody, SP-B antibody, AI562151 antibody, SF-B antibody, Sftp-3 antibody, Sftp3 antibody, Sp-b antibody, SFTPB antibody, sftpb antibody, xSP-B antibody, surfactant protein B antibody, surfactant associated protein B antibody, surfactant, pulmonary-associated protein B L homeolog antibody, SFTPB antibody, Sftpb antibody, sftpb.L antibody
    Background
    SFTPB is the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins. See also SFTPA1, SFTPC, and SFTPD. The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PSP-B, SFTB3, SFTP3, SMDP1, SP-B
    Protein Interaction Partner: CTSH,
    Protein Size: 381
    Molecular Weight
    42 kDa
    Gene ID
    6439
    NCBI Accession
    NM_000542, NP_000533
    UniProt
    B2RC55
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