FBP1 antibody (N-Term)

Catalog No. ABIN2776794

Product Details anti-FBP1 Antibody

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YVVCFDPLDG SSNIDCLVSV GTIFGIYRKK STDEPSEKDA LQPGRNLVAA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 86%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against FBP1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FBP1 antibody (ABIN2776794)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Target Details for FBP1

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Alternative Name: FBP1 (FBP1 Products)

Synonyms: FBP antibody, Fbp-2 antibody, Fbp2 antibody, Fbp3 antibody, FBP1 antibody, fbp2 antibody, Fdp antibody, CG10611 antibody, CG31692 antibody, Dmel\\CG31692 antibody, FbPase antibody, fbp1 antibody, cb598 antibody, fb57b01 antibody, zgc:64127 antibody, id:ibd1091 antibody, wu:fb17g10 antibody, wu:fb57b01 antibody, fdp antibody, xcc-b100_0105 antibody, fbp1l antibody, fk92h02 antibody, wu:fk92h02 antibody, zgc:64096 antibody, fbp antibody, fbp1.S antibody, fructose-bisphosphatase 1 antibody, fructose bisphosphatase 1 antibody, Fructose-1,6-bisphosphatase antibody, fructose-1,6-bisphosphatase antibody, fructose-1,6-bisphosphatase 1 antibody, fructose-bisphosphatase class I antibody, fructose-1,6-bisphosphatase 1b antibody, fbp antibody, fructose-1,6-bisphosphatase 1a antibody, fructose-bisphosphatase 1 L homeolog antibody, FBP1 antibody, Fbp1 antibody, fbp1 antibody, LOC100136618 antibody, RR_RS07410 antibody, fbp antibody, fbp1b antibody, fbp1a antibody, fbp1.L antibody

Background: Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
Alias Symbols: FBP
Protein Interaction Partner: FBP2, FBP1, BIN1, KLRC2, ASL, UBC, POT1, TERF1, PARK2, HDAC6, PTK2, DYNC1I1, CSNK1E, BCL2L1, LNX1, PCNXL4, ATP5J2, ASCC2, RNF183, HSPA8, FXR2, ACTN1,
Protein Size: 338

Molecular Weight: 37 kDa

Gene ID: 2203

NCBI Accession: NM_000507, NP_000498

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport