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ALDOB antibody (Middle Region)

ALDOB Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776767
  • Target See all ALDOB Antibodies
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    Binding Specificity
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 61
    • 33
    • 33
    • 16
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog, Sheep
    Host
    • 51
    • 10
    Rabbit
    Clonality
    • 53
    • 7
    Polyclonal
    Conjugate
    • 33
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALDOB antibody is un-conjugated
    Application
    • 54
    • 26
    • 13
    • 9
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
    Characteristics
    This is a rabbit polyclonal antibody against ALDOB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ALDOB
    Top Product
    Discover our top product ALDOB Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 364 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    Alternative Name
    ALDOB (ALDOB Products)
    Synonyms
    aldb antibody, aldo2 antibody, xaldb antibody, ALDOB antibody, aldob antibody, ALDB antibody, ALDO2 antibody, Aldo-2 antibody, Aldo2 antibody, BC016435 antibody, LIV10 antibody, fb25f09 antibody, wu:fb25f09 antibody, aldolase B antibody, aldolase, fructose-bisphosphate B antibody, aldolase, fructose-bisphosphate B S homeolog antibody, aldolase b, fructose-bisphosphate antibody, aldolase B, fructose-bisphosphate antibody, xaldb antibody, aldob antibody, aldob.S antibody, ALDOB antibody, Aldob antibody
    Background
    Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13 ) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ALDB, ALDO2
    Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, MUC20, AGXT2, TXN2, UBC, HIVEP1, ALDOA, APP, HSPA8, ALDOB, ATP6V1E1,
    Protein Size: 364
    Molecular Weight
    39 kDa
    Gene ID
    229
    NCBI Accession
    NM_000035, NP_000026
    UniProt
    P05062
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