WDR5 antibody (C-Term)

Catalog No. ABIN2776738

Product Details anti-WDR5 Antibody

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against WDR5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5 (WDR5 Products)

Synonyms: BIG-3 antibody, SWD3 antibody, 2410008O07Rik antibody, AA408785 antibody, AA960360 antibody, Big antibody, Big-3 antibody, zgc:56591 antibody, zgc:76895 antibody, wu:fk47f04 antibody, wdr5-a antibody, MGC80538 antibody, wdr5-b antibody, MGC81485 antibody, big-3 antibody, swd3 antibody, xwdr5 antibody, WDR5B antibody, WD repeat domain 5 antibody, WD repeat domain 5 L homeolog antibody, WD repeat domain 5 S homeolog antibody, WDR5 antibody, Wdr5 antibody, wdr5 antibody, wdr5.L antibody, wdr5.S antibody

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: BIG-3, SWD3
Protein Interaction Partner: RUSC1-AS1, SSX2IP, ZXDC, MBIP, CXXC1, SETD1A, HSF2, PRMT5, NFE4, KMT2D, ING2, HDAC1, SENP3, UBC, BMI1, SRPK2, CSNK2A2, CSNK1E, KDM6B, KDM6A, NEDD8, KMT2A, BARD1, UNC45A, VPS35, CSE1L, ATP6V1B2, APP, ASH2L, USP1, TTK, PPP1CB, HCFC1, TADA3, KAT2B, TADA2A, M
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 11091

NCBI Accession: NM_017588, NP_060058

UniProt: Q5M786