Vangl1 antibody (N-Term)

Catalog No. ABIN2776734

Product Details anti-Vangl1 Antibody

Target: Vangl1 (Vang-Like 1 (Vangl1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vangl1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YSGYSYYSSH SKKSHRQGER TRERHKSPRN KDGRGSEKSV TIQPPTGEPL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VANGL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Vangl1

Target: Vangl1 (Vang-Like 1 (Vangl1))

Alternative Name: VANGL1 (Vangl1 Products)

Background: This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants.
Alias Symbols: KITENIN, LPP2, MGC5338, STB2, STBM2
Protein Interaction Partner: FBXW11, UBC, SRPK1, THAP2, SMYD3, NT5C3A, RAPGEF5, GMFG, KBTBD7, CD82, DVL2, DVL3, DVL1,
Protein Size: 524

Molecular Weight: 60 kDa

Gene ID: 81839

NCBI Accession: NM_138959, NP_620409

UniProt: Q8TAA9

Pathways: WNT Signaling