FZD5 antibody (Middle Region)

Catalog No. ABIN2776705

Product Details anti-FZD5 Antibody

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CYLYEQHYRE SWEAALTCAC PGHDTGQPRA KPEYWVLMLK YFMCLVVGIT

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against FZD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FZD5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 585 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FZD5

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Alternative Name: FZD5 (FZD5 Products)

Synonyms: C2orf31 antibody, HFZ5 antibody, 5330434N09Rik antibody, AI427138 antibody, Fz-5 antibody, Fz5 antibody, mFz5 antibody, Xfz5 antibody, frizzled5 antibody, frizzled5a antibody, fz5 antibody, fzd5-A antibody, fz2 antibody, fz8c antibody, fzd8c antibody, zg02 antibody, frizzled class receptor 5 antibody, frizzled class receptor 5 S homeolog antibody, FZD5 antibody, Fzd5 antibody, fzd5.S antibody, fzd5 antibody

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
Alias Symbols: C2orf31, DKFZP434E2135, HFZ5, MGC129692
Protein Interaction Partner: LRP6, UBTD1, LZTFL1, ABI3BP, RGS2, RPS6KA6, GSK3B, UBC, Ror2, GOPC, WNT7A, WNT5A,
Protein Size: 585

Molecular Weight: 62 kDa

Gene ID: 7855

NCBI Accession: NM_003468, NP_003459

UniProt: Q13467

Pathways: WNT Signaling