MBNL1 antibody (Middle Region)

Catalog No. ABIN2776697

Product Details anti-MBNL1 Antibody

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AMTQSAVKSL KRPLEATFDL GIPQAVLPPL PKRPALEKTN GATAVFNTGI

Predicted Reactivity: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MBNL1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBNL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 343 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MBNL1 antibody (ABIN2776697)

Coram, Stillwagon, Guggilam, Jenkins, Swanson, Ladd: "Muscleblind-like 1 is required for normal heart valve development in vivo." in: BMC developmental biology, Vol. 15, pp. 36, (2015) (PubMed).

Target Details for MBNL1

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Alternative Name: MBNL1 (MBNL1 Products)

Synonyms: MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody

Background: MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.
Alias Symbols: EXP, MBNL, EXP35, EXP40, EXP42
Protein Interaction Partner: DAB1, AES, AEN, UBC, ABI3BP, ZNHIT3, VCAM1, ITGA4, IDH3A, FN1, TIAL1, APP, BIN1, ITSN2, DDX17, HNRNPL, HNRNPK, HNRNPH3, HNRNPH2, HNRNPH1, HNRNPF, HNRNPA2B1, DHX9, DDX5,
Protein Size: 343

Molecular Weight: 38 kDa

Gene ID: 4154

NCBI Accession: NM_021038

UniProt: Q86VM6

Pathways: Ribonucleoprotein Complex Subunit Organization