DDX47 antibody (C-Term)

Catalog No. ABIN2776687

Product Details anti-DDX47 Antibody

Target: DDX47 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 47 (DDX47))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Guinea Pig, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AQRFARMELR EHGEKKKRSR EDAGDNDDTE GAIGVRNKVA GGKMKKRKGR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against DDX47. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DDX47

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 455 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DDX47 antibody (ABIN2776687)

Huang, Chien, Huang, Ni, Chang, Ho, Lee, Hwu: "Viral infections and prolonged fever after liver transplantation in young children with inborn errors of metabolism." in: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 104, Issue 9, pp. 623-9, (2005) (PubMed).

Target Details for DDX47

Target: DDX47 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 47 (DDX47))

Alternative Name: DDX47 (DDX47 Products)

Synonyms: ddx47 antibody, DDX47 antibody, E4-DBP antibody, HQ0256 antibody, MSTP162 antibody, RRP3 antibody, 4930588A18Rik antibody, C77285 antibody, DEAD-box helicase 47 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 antibody, DEAD-box helicase 47 L homeolog antibody, DDX47 antibody, ddx47 antibody, Ddx47 antibody, ddx47.L antibody

Background: DDX47 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: RRP3, E4-DBP, HQ0256, MSTP162
Protein Interaction Partner: UBC, EED, rev, PARK2, SRPK1, MLH1, KRAS, FN1, APP, EXOSC4, CAND1, PRNP, SUMO1, HDGF, SUMO2, HDAC5, SART3, Rrp1b,
Protein Size: 455

Molecular Weight: 50 kDa

Gene ID: 51202

NCBI Accession: NM_016355, NP_057439

UniProt: Q9H0S4