HNRNPA3 antibody (N-Term)

Catalog No. ABIN2776678

Product Details anti-HNRNPA3 Antibody

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HNRPA3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 378 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HNRNPA3 antibody (ABIN2776678)

Papadopoulou, Patrinou-Georgoula, Guialis: "Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes." in: Biochimica et biophysica acta, Vol. 1804, Issue 4, pp. 692-703, (2010) (PubMed).

Süss, Czupalla, Winter, Pursche, Knoch, Schroeder, Hoflack, Solimena: "Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 3, pp. 393-408, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for HNRNPA3

Target: HNRNPA3 (Heterogeneous Nuclear Ribonucleoprotein A3 (HNRNPA3))

Alternative Name: HNRPA3 (HNRNPA3 Products)

Synonyms: 2610510D13Rik antibody, D10S102 antibody, FBRNP antibody, HNRPA3 antibody, 2410013L13Rik antibody, 2610209F03Rik antibody, Hnrpa3 antibody, zgc:153703 antibody, DKFZp469I0118 antibody, heterogeneous nuclear ribonucleoprotein A3 antibody, heterogeneous nuclear ribonucleoprotein A3 S homeolog antibody, heterogeneous nuclear ribonucleoprotein A1 antibody, hypothetical protein antibody, HNRNPA3 antibody, Hnrnpa3 antibody, hnrnpa3.S antibody, HNRNPA1 antibody, hnrnpa3 antibody, ARCVE_RS10260 antibody

Background: HNRPA3 plays a role in cytoplasmic trafficking of RNA. It binds to the cis-acting response element(A2RE) and may be involved in pre-mRNA splicing
Alias Symbols: FBRNP, HNRPA3, D10S102, 2610510D13Rik
Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, LIN28A, SUMO1, NEDD8, MDM2, RPA3, RPA2, RPA1, WWOX, ZBTB1, RNF2, EED, rev, PARK2, TARDBP, IGSF8, ICAM1, CD81, PAN2, TP63, WHSC1, VCAM1, ITGA4, IL7R, IFIT3, FN1, ESR1, SMURF1, YWHAE, RPS28, RPS13, RPLP2, RAB1A, PTBP1, HSPA8, HSPA5
Protein Size: 378

Molecular Weight: 42 kDa

Gene ID: 220988

NCBI Accession: NM_194247, NP_919223

UniProt: P51991