RAVER1 antibody (N-Term)

Catalog No. ABIN2776619

Product Details anti-RAVER1 Antibody

Target: RAVER1 (Ribonucleoprotein, PTB-Binding 1 (RAVER1))

Binding Specificity: N-Term

Reactivity: Human, Guinea Pig, Rabbit, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAVER1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VTHRPPLSPK SGAEVEAGDA AERRAPEEEL PPLDPEEIRK RLEHTERQFR

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against RAVER1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RAVER1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 606 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAVER1

Target: RAVER1 (Ribonucleoprotein, PTB-Binding 1 (RAVER1))

Alternative Name: RAVER1 (RAVER1 Products)

Synonyms: MGC83237 antibody, zgc:112236 antibody, RAVER1 antibody, Raver1h antibody, 1300006N24Rik antibody, AA050359 antibody, mKIAA1978 antibody, hypothetical protein antibody, ribonucleoprotein, PTB-binding 1 S homeolog antibody, ribonucleoprotein, PTB-binding 1 antibody, ribonucleoprotein, PTB binding 1 antibody, Raver1 antibody, raver1.S antibody, raver1 antibody, RAVER1 antibody

Background: RAVER1 contains 3 RRM (RNA recognition motif) domains. It cooperates with PTBP1 to modulate regulated alternative splicing events and promotes exon skipping. It cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Protein Interaction Partner: FUS, NEDD1, CEP76, CEP72, HAUS2, CEP250, AURKB, TUBG1, TP53, PPP2R1A, LGALS3BP, CDKN1A, CDC20, AIRE, STAU1, UBC, RPA3, RPA2, RPA1, WHSC1, VCAM1, FN1, MCAT, DYNLT1, SDHA, PHKB, ABCC1, AK2, ELAVL1, SUMO2, Cnot3, TERF2, PTBP1, VCL, ACTN1, ACTN2,
Protein Size: 606

Molecular Weight: 67 kDa

Gene ID: 125950

NCBI Accession: NM_133452, NP_597709

UniProt: Q8IY67