SRSF12 antibody (Middle Region)

Catalog No. ABIN2776616

Product Details anti-SRSF12 Antibody

Target: SRSF12 (serine/arginine-Rich Splicing Factor 12 (SRSF12))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Guinea Pig, Horse, Rabbit, Dog, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RSRSKSLQKR SKSIGKSQSS SPQKQTSSGT KSRSHGRHSD SIARSPCKSP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SRrp35. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRrp35

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 261 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SRSF12 antibody (ABIN2776616)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Target Details for SRSF12

Target: SRSF12 (serine/arginine-Rich Splicing Factor 12 (SRSF12))

Alternative Name: SRrp35 (SRSF12 Products)

Synonyms: RP11-63L7.3 antibody, SFRS13B antibody, SFRS19 antibody, SRrp35 antibody, B830039L16 antibody, Sfrs13b antibody, Srrp antibody, Srsf13b antibody, serine and arginine rich splicing factor 12 antibody, serine/arginine-rich splicing factor 12 antibody, SRSF12 antibody, Srsf12 antibody

Background: SRrp35 is a splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation.
Alias Symbols: FLJ14459, FLJ33484, FLJ41221, RP11-63L7.3, SFRS19, SRrp35, SFRS13B
Protein Interaction Partner: SRPK2, SRPK1, CDK6, MAGOH,
Protein Size: 261

Molecular Weight: 30 kDa

Gene ID: 135295

NCBI Accession: NM_080743, NP_542781

UniProt: Q8WXF0

Pathways: Ribonucleoprotein Complex Subunit Organization