SRSF10 antibody (C-Term)

Catalog No. ABIN2776611

Product Details anti-SRSF10 Antibody

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TDSKTHYKSG SRYEKESRKK EPPRSKSQSR SQSRSRSKSR SRSWTSPKSS

Predicted Reactivity: Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUSIP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 262 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Alternative Name: FUSIP1 (SRSF10 Products)

Synonyms: FUSIP1 antibody, SFRS13A antibody, FUSIP2 antibody, NSSR antibody, SFRS13 antibody, SRp38 antibody, SRrp40 antibody, TASR antibody, TASR1 antibody, TASR2 antibody, Fusip1 antibody, NSSR1 antibody, NSSR2 antibody, Nssr antibody, Sfrs13a antibody, Srsf13a antibody, fusip1 antibody, fusip2 antibody, nssr antibody, sfrs13 antibody, sfrs13a antibody, srp38 antibody, srrp40 antibody, tasr antibody, tasr1 antibody, tasr2 antibody, serine and arginine rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 S homeolog antibody, SRSF10 antibody, Srsf10 antibody, srsf10.S antibody

Background: FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.
Alias Symbols: FUSIP2, NSSR, SFRS13, SRp38, SRrp40, TASR, TASR1, TASR2, FUSIP1, SFRS13A
Protein Interaction Partner: STAU1, WWOX, SUZ12, EED, RNF2, EZH2, HECW2, TRA2B, SRSF4, SRSF1, CSNK2A1, EIF4A3, MAGOH, PAXIP1, BARD1, SAP18, VTN, TCOF1, SRSF6, S100A9, PRKDC, NHP2L1, NFIA, SEPT2, MSH2, IK, EPRS, DHX15, BCAS2, TRIM55, THOC6, ZNF687, SMU1, TRMT112, TRA2A, PHGDH, NCSTN,
Protein Size: 262

Molecular Weight: 29 kDa

Gene ID: 10772

NCBI Accession: NM_054016, NP_473357

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization